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Ampicillin Mechanism of action
Ampicillin is a medicament that stops the growth of bacteria in your body. This medicine is used to treat infections that result from infection with certain types of bacteria. This medication can be used as a separate drug or could be prescribed by a doctor as a combination therapy. In other words, you will take Ampicillin with other pills. This medicine belongs to a certain class called penicillins. The class of medicines is the belonging of certain drugs to one type that works in one way (kills harmful bacteria or prevents their reproduction in the body).
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The dosage of this medicine will always be individual. The doctor should not only study the medical condition of the patient but also find out other factors that will affect the appointment of a specific dosage. The doctor should know how the patient will respond to the first dosage, his age, the type of disease that needs to be treated; the patient’s other diseases and the tolerance of the active components of the drug. This medicine may be prescribed for adults and children. It is also important to consider that the kidneys of older people do not work well - this will also affect the prescribed dose. These are some examples of dosages for treating certain types of infections.
- For the treatment of urinary tract infections:
The dosage will be 500 mg, which the patient will take 4 times a day.
- For urinary tract infections:
The dosage will be 100 mg per 1 kg, which the patient will divide into 4 identical dosages per day.
- For the treatment of gonorrhea:
The dose will be 3.5 grams - the patient should take this once.
- For the treatment of gastrointestinal infections:
The standard dosage will be 500 mg which must be divided into 4 times.
The dosage for meningitis will be individual for children and adults. The doctor determines the level of infection and the patient's response to treatment with the first dosage. Also, the initial dosage can be reduced if the patient does not respond well to the active substances in the medication. If the infection is poorly treated, the doctor may increase the dosage.
Ampicillin side effects
Ampicillin in capsules can give certain side effects but it does not cause drowsiness. Among the frequent side effects are diarrhea, skin rash, nausea, or vomiting. Such symptoms can be called simple or weak and they disappear in a few days. If their form becomes stronger, then the patient should talk with his MD to reduce the dosage or cancel the medicament. If you experience severe side effects, then call your doctor or ambulance.
It is also important to remember that people may have an allergic reaction to the active substances of Ampicillin. It is also important to talk with your doctor about your dosage. If the patient has an allergic reaction, then the symptoms may be similar to flu, give a fever, purple rash, itching, or a red rash that can spread throughout the body. Serious side effects can also cause blisters, diarrhea with fever, and cramping in the stomach.
In addition to an allergic reaction, this medication has other contraindications. That is, these are groups of people with certain diseases and characteristics of the body when the dosage of Ampicillin would be small or prohibited. These are people with diabetes, kidney disease, patients with syphilis or gonorrhea. Pregnant women may take this medicine in rare cases, but it is forbidden to take it before planning a pregnancy. If you find out that you are pregnant and are still taking this medicament, call your doctor. Studies have shown mixed results; sometimes taking this drug could harm the normal development of the fetus.
It is also important to remember the characteristics of the body of the elderly; the dosage will also be individual. The kidneys of older people work more slowly so the drug will stay in the body longer. Ampicillin may be prescribed for children but the dosage will be the lowest. The kidneys of children are also weak because they are still developing. This can lead to a slow exit of the drug from the body and the appearance of side effects.
Ampicillin vs Amoxicillin
Both of these drugs are based on the penicillin core and they have similar beta-lactam ring structures. Their functions include the antibacterial effect that is in all medicines of the penicillin class. Ampicillin has an individual dosage and is not prescribed for all patient groups. Amoxicillin has a standard dose and can be prescribed to people even with mild renal failure. This drug has a pleasant taste, low price and could be used by people who are not very sensitive to its components. Ampicillin is more expensive, and the list of precautions is quite large. Amoxicillin shows good results when given to children, and Ampicillin should be prescribed based on many factors.
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Medically reviewed by Dr. Josette Davignon
Last updated: 28.09.2022